Mugwort (Artemisia vulgaris) is a flowering plant native to northern Europe, Asia, and parts of North America. This sage-colored plant has seen continuous use in many cultures throughout the world as a medicinal, spiritual, and culinary ingredient since at least the Iron Age. In contemporary culture mugwort is commonly found in foods and drinks, and remains a common ingredient in Chinese, Japanese, and Korean traditional medicine, where the leaves are used directly as a food or to obtain oil extracts or tinctures. The roots, leaves, stems, and blossoms of the mugwort plant are all used in folk medicine to make tinctures, extracts, tonics, teas, powders, and essential oils. This article describes medical uses, possible side effects, and how to select and safely use mugwort.